abstract：OBJECTIVE:Radioiodide is commonly used to diagnose and treat hyperthyroidism and thyroid carcinoma. However, we could not find any experimental data that strictly compared the biodistribution and thyroid uptake of radioactive iodide between the oral and intravenous (iv) routes with time. This prompted us to compare (12...

journal_title：Annals of nuclear medicine

authors： Kurosawa H,Sakurai K,Hasegawa H,Uchida K,Kasahara H,Minamizawa T,Nakajo M,Nakajo M

更新日期：2014-12-01 00:00:00

abstract：OBJECTIVE:Estimation of nonlinear micro-parameters is a computationally demanding and fairly challenging process, since it involves the use of rather slow iterative nonlinear fitting algorithms and it often results in very noisy voxel-wise parametric maps. Direct reconstruction algorithms can provide parametric maps wi...

journal_title：Annals of nuclear medicine

authors： Angelis GI,Matthews JC,Kotasidis FA,Markiewicz PJ,Lionheart WR,Reader AJ

更新日期：2014-11-01 00:00:00

abstract：BACKGROUND:The liver itself regenerates after hepatectomy but little is known about how much hepatic function recovers during the regeneration. The liver uptake value (LUV), calculated from Tc-99m-labeled galactosyl-human-serum-albumin ((99m)Tc-GSA) SPECT/CT fused images, is reliable and useful for evaluating hepatic f...

journal_title：Annals of nuclear medicine

authors： Yoshida M,Shiraishi S,Sakamoto F,Beppu T,Utsunomiya D,Okabe H,Tomiguchi S,Baba H,Yamashita Y

更新日期：2014-10-01 00:00:00

abstract：OBJECTIVE:The purpose of this study was to investigate the diagnostic performance of postoperative fluorine-18 fluoro-2-deoxy-D-glucose ((18)F-FDG) positron emission tomography/computed tomography (PET/CT) as a surveillance modality for advanced gastric cancer patients who were asymptomatic and negative by conventional...

journal_title：Annals of nuclear medicine

authors： Lee DY,Lee CH,Seo MJ,Lee SH,Ryu JS,Lee JJ

更新日期：2014-10-01 00:00:00

abstract：OBJECTIVE:We developed a bubble point test kit and investigated the bubble point test of a 0.22-μm membrane filter used for the sterilizing filtration of [(18)F]FDG, [(11)C]MET and [(11)C]PIB. The bubble point test of the Millex-GS vented filter was often difficult due to air leakage from the vented portion of this fil...

journal_title：Annals of nuclear medicine

authors： Hayashi K,Douhara K,Kashino G

更新日期：2014-07-01 00:00:00

abstract：OBJECTIVE:Uptake value in quantitative PET imaging is biased due to the presence of CT contrast agents when using CT-based attenuation correction. Our aim was to examine spectral CT imaging to suppress inaccuracy of 511 keV attenuation map in the presence of multiple nanoparticulate contrast agents. METHODS:Using a si...

journal_title：Annals of nuclear medicine

authors： Ghadiri H,Shiran MB,Soltanian-Zadeh H,Rahmim A,Zaidi H,Ay MR

更新日期：2014-07-01 00:00:00

abstract：OBJECTIVE:To investigate the potential role of Tc-99m depreotide (Tc-DEPR) in the preoperative lymph node (N) staging of non-small-cell lung cancer (NSCLC). METHODS:Sixty-one patients with NSCLC at the potentially operable stage were enrolled and underwent scintigraphy before surgery (n=56) or mediastinoscopy (n=5). I...

journal_title：Annals of nuclear medicine

authors： Apostolopoulos DJ,Koletsis EN,Spyridonidis T,Paschali A,Papandrianos N,Stamou E,Vassilakos PJ,Dougenis D

更新日期：2014-06-01 00:00:00

abstract：OBJECTIVE:We performed a bibliometric analysis of scientific publications focused on positron emission tomography (PET) over a 10-year period. METHODS:The MEDLINE and ISI Web of Knowledge databases were searched for English language original articles focused on PET in SCI/SCIE-indexed journals in 2002, 2007, and 2012....

journal_title：Annals of nuclear medicine

authors： Baek S,Yoon DY,Min KJ,Lim KJ,Seo YL,Yun EJ

更新日期：2014-06-01 00:00:00

abstract：OBJECTIVE:Accurate and validated methods for estimating regional PET image noise are helpful for optimizing image processing. The bootstrap is a data-based simulation method for statistical inference, which can be used to estimate the PET image noise without repeated measurements. The aim of this study was to experimen...

journal_title：Annals of nuclear medicine

authors： Ibaraki M,Matsubara K,Nakamura K,Yamaguchi H,Kinoshita T

更新日期：2014-02-01 00:00:00

abstract：OBJECTIVE:Dopamine transporter imaging with SPECT is a valuable tool for both clinical routine and research studies. Semi-quantitative analysis plays a key role in interpreting the scans, but is dependent on numerous factors, rotational radius being one of them. This study systematically evaluates the potential influen...

journal_title：Annals of nuclear medicine

authors： Koch W,Bartenstein P,la Fougère C

更新日期：2014-02-01 00:00:00

abstract：OBJECTIVES:Breast cancer is the most common malignancy for females worldwide. This study was to evaluate the application of dual-phase breast-specific gamma imaging (BSGI) in detecting primary breast cancer. METHODS:Seventy-six patients with indeterminate breast lesions that underwent dual-phase BSGI enrolled in this ...

journal_title：Annals of nuclear medicine

authors： Tan H,Jiang L,Gu Y,Xiu Y,Han L,Wu P,Zhang H,Shi H

更新日期：2014-01-01 00:00:00

abstract：OBJECTIVE:To design, build, and evaluate an animal PET scanner, which can be used with non-human primates under conscious condition, incorporating flat-panel position-sensitive photomultiplier tubes (PS-PMTs). METHODS:The system contains 30 detector modules, each having two PS-PMTs and 16×18 lutetium–yttrium oxyortho-...

journal_title：Annals of nuclear medicine

authors： Okamoto T,Ote K,Sakai K,Noda A,Shimizu K,Masuda K,Ohmura T,Watanabe M

更新日期：2014-01-01 00:00:00

abstract：OBJECTIVE:In this study, the feasibility and kinetic characteristics of the (68)Ga-NOTA-RGD, a recently developed RGD peptide agent, were investigated for atherosclerosis imaging in comparison with (18)FDG. METHODS:ApoE(-/-) mice were fed a high-fat diet for more than 20 weeks. To evaluate the feasibility, tissue upta...

journal_title：Annals of nuclear medicine

authors： Paeng JC,Lee YS,Lee JS,Jeong JM,Kim KB,Chung JK,Lee DS

更新日期：2013-11-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to measure the apparent diffusion coefficient (ADC) value at the region with the highest FDG uptake using sequential (18)F-FDG PET and MRI, and to correlate it with the histological grade of invasive ductal carcinoma (IDC) of the breast. METHODS:A retrospective study was conducted o...

journal_title：Annals of nuclear medicine

authors： Byun BH,Noh WC,Lim I,Lee SS,Cho AR,Park JA,Kim KM,Kim HA,Kim EK,Kim BI,Choi CW,Lim SM

更新日期：2013-10-01 00:00:00

abstract：OBJECTIVE:One mechanism that may be responsible for drug resistance in epilepsy is the upregulation of P-glycoprotein (P-gp), a drug efflux pump, at the epileptogenic focus. In this study, we sought to evaluate the potential of a recently developed P-gp PET radiotracer, [(11)C]N-desmethyl-loperamide ([(11)C]dLop), for ...

journal_title：Annals of nuclear medicine

authors： Farwell MD,Chong DJ,Iida Y,Bae SA,Easwaramoorthy B,Ichise M

更新日期：2013-08-01 00:00:00

abstract：:Whole-body positron emission tomography/computed tomography (PET/CT) with [(11)C]- and [(18)F]-labeled choline derivates has emerged as a promising molecular imaging modality for the evaluation of prostate cancer. (11)C- and (18)F-choline PET/CT are used successfully for restaging prostate cancer in patients with bioc...

journal_title：Annals of nuclear medicine

authors： Kitajima K,Murphy RC,Nathan MA

更新日期：2013-08-01 00:00:00

abstract：AIM:The purpose of the study was to determine the lung toxicity caused by amiodarone (AD) and bleomycin (BLM) in rats, by means of Tc-99m HMPAO lung scintigraphy. METHODS:Thirty albino rats were randomly divided into five groups. After AD or BLM was dissolved with isotonic saline (SF), a 0.5 ml solution was applied to...

journal_title：Annals of nuclear medicine

authors： Gumuser G,Vural K,Varol T,Parlak Y,Tuglu I,Topal G,Sayit E

更新日期：2013-08-01 00:00:00

abstract：PURPOSE:This study aimed at demonstrating the feasibility of retrospectively fused (18)F FDG-PET and MRI (PET/MRI fusion image) in diagnosing pancreatic tumor, in particular differentiating malignant tumor from benign lesions. In addition, we evaluated additional findings characterizing pancreatic lesions by FDG-PET/MR...

journal_title：Annals of nuclear medicine

authors： Nagamachi S,Nishii R,Wakamatsu H,Mizutani Y,Kiyohara S,Fujita S,Futami S,Sakae T,Furukoji E,Tamura S,Arita H,Chijiiwa K,Kawai K

更新日期：2013-07-01 00:00:00

abstract：OBJECTIVE:To determine the optimal accumulation time for three-dimensional positron emission tomography (3D-PET) with (18)F-2-fluoro-2-deoxy-D-glucose ((18)F-FDG) to detect the brain uptake pattern typical of Alzheimer's disease (AD). METHODS:Patients with mild AD or amnestic mild cognitive impairment (MCI) and normal...

journal_title：Annals of nuclear medicine

authors： Takahashi R,Ishii K,Senda M,Ito K,Ishii K,Kato T,Makishi Y,Nishio T,Ikari Y,Iwatsubo T,Japanese Alzheimer’s Disease Neuroimaging Initiative.

更新日期：2013-06-01 00:00:00

abstract：OBJECTIVE:Epidermal growth factor receptor tyrosine kinase (EGFR-TK) represents an attractive target for tumor diagnosis agents. Previously, radioiodinated 4-(3-iodophenoxy)-6,7-diethoxyquinazoline (PHY) was reported to possess good characteristics as a tumor imaging agent. We have explored the feasibility of developin...

journal_title：Annals of nuclear medicine

authors： Hirata M,Kanai Y,Naka S,Yoshimoto M,Kagawa S,Matsumuro K,Katsuma H,Yamaguchi H,Magata Y,Ohmomo Y

更新日期：2013-06-01 00:00:00

abstract：OBJECTIVES:Advances in radiopharmaceuticals and clinical understanding have escalated the use of intraoperative gamma probes in surgery. However, most probes on the market are non-imaging gamma probes that suffer from the lack of ancillary information of the surveyed tissue area. We have developed a novel, hand-held di...

journal_title：Annals of nuclear medicine

authors： Singh B,Stack BC Jr,Thacker S,Gaysinskiy V,Bartel T,Lowe V,Cool S,Entine G,Nagarkar V

更新日期：2013-04-01 00:00:00

abstract：PURPOSE:Treatment effect of radiofrequency ablation (RFA) is traditionally accomplished with MRI and/or CT. The aim of the study was to assess the role of FDG-PET in post RFA hepatic tumor evaluation, in comparison with MRI and CT. MATERIALS AND METHODS:28 patients (33 hepatic RFA lesions) who had post RFA FDG-PET wit...

journal_title：Annals of nuclear medicine

authors： Chen W,Zhuang H,Cheng G,Torigian DA,Alavi A

更新日期：2013-01-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to evaluate the value of breast-specific gamma imaging (BSGI) as compared with mammography (MMG) and ultrasonography (US). METHODS:This study retrospectively enrolled 121 women with breast cancer (45.0 ± 8.1 years) and dense breasts (breast density >50 %). All patients underwent pre...

journal_title：Annals of nuclear medicine

authors： Kim BS,Moon BI,Cha ES

更新日期：2012-12-01 00:00:00

abstract：AIM:Computer-aided diagnosis (CAD) software for bone scintigrams have recently been introduced as a clinical quality assurance tool. The purpose of this study was to compare the diagnostic accuracy of two CAD systems, one based on a European and one on a Japanese training database, in a group of bone scans from Japanes...

journal_title：Annals of nuclear medicine

authors： Horikoshi H,Kikuchi A,Onoguchi M,Sjöstrand K,Edenbrandt L

更新日期：2012-10-01 00:00:00

abstract：OBJECTIVE:Because of the urinary excretion of fluorine-18 fluorodeoxyglucose ((18)F-FDG), FDG-PET or PET/CT is thought of little value in patients with bladder cancer. The purpose of our study was to investigate the value of (18)F-FDG PET/CT with additional pelvic images in detection of recurrent bladder cancers. METH...

journal_title：Annals of nuclear medicine

authors： Yang Z,Cheng J,Pan L,Hu S,Xu J,Zhang Y,Wang M,Zhang J,Ye D,Zhang Y

更新日期：2012-08-01 00:00:00

abstract：OBJECTIVE:In high-risk patients with left bundle-branch block (LBBB), functional but not perfusion parameters yield incremental prognostic information. The aim of our study was to evaluate the prognostic value of gated single photon emission computed tomography (SPECT) in low-intermediate risk LBBB patients. METHODS:O...

journal_title：Annals of nuclear medicine

authors： Fovino LN,Saladini G,Mormino GP,Saladini F,Razzolini R,Evangelista L

更新日期：2012-08-01 00:00:00

abstract：PURPOSE:Tumor recurrence of colorectal cancers (CRC) is generally followed up by analyses of the serum carcinoembryonic antigen (CEA) levels. However, recent evidence suggests that tumor recurrence can also be visualized by 18F-fluoro-deoxyglucose emission tomography/computed tomography (FDG-PET/CT) in patients with no...

journal_title：Annals of nuclear medicine

authors： Sanli Y,Kuyumcu S,Ozkan ZG,Kilic L,Balik E,Turkmen C,Has D,Isik G,Asoglu O,Kapran Y,Adalet I

更新日期：2012-08-01 00:00:00

abstract：:We report a rare case of intravascular large B-cell lymphoma (IVLBCL) with diffuse fluorodeoxyglucose (FDG) uptake in the lung by (18)FDG-positron emission tomography/computed tomography (PET/CT). CT showed nodular shadow, whereas diffuse FDG uptake in PET/CT suggested IVLBCL in the lung. A random skin biopsy provided...

journal_title：Annals of nuclear medicine

authors： Yamashita H,Suzuki A,Takahashi Y,Kubota K,Kano T,Mimori A

更新日期：2012-07-01 00:00:00

abstract：:To systematically review published data on the role of positron emission tomography (PET) or PET/computed tomography (PET/CT) using either Carbon-11 ((11)C) or Fluorine-18 ((18)F) choline tracer in tumors other than prostatic cancer. A comprehensive literature search of studies published in PubMed/MEDLINE and Embase d...

journal_title：Annals of nuclear medicine

authors： Treglia G,Giovannini E,Di Franco D,Calcagni ML,Rufini V,Picchio M,Giordano A

更新日期：2012-07-01 00:00:00

abstract：PURPOSE:The presence of central lymph node (LN) metastasis increases the risk of cervical LN recurrence or distant metastasis in patients with papillary thyroid microcarcinoma (PTMC). We investigated the value of preoperative (18)F-fluoro-2-deoxy-D-glucose-positron emission tomography (FDG PET)-computerized tomography ...

journal_title：Annals of nuclear medicine

authors： Byun BH,Jeong UG,Hong SP,Min JJ,Chong A,Song HC,Bom HS

更新日期：2012-07-01 00:00:00

abstract：OBJECTIVE:Epidermal growth factor receptor tyrosine kinase (EGFR-TK) represents an attractive target for tumor diagnosis agents. Previously, the radioiodinated 4-(3-iodoanilino)-6,7-diethoxyquinazoline ([(125)I]m-IPQ) has been reported to possess good characteristics as a tumor imaging agent; however, it was also found...

journal_title：Annals of nuclear medicine

authors： Hirata M,Kanai Y,Naka S,Matsumuro K,Kagawa S,Yoshimoto M,Ohmomo Y

更新日期：2012-06-01 00:00:00

abstract：OBJECTIVE:Praseodymium-142 [T 1/2 = 19.12 h, [Formula: see text] = 2.162 MeV (96.3%), Eγ = 1575 keV (3.7%)] is one of the (141)Pr radioisotopes. Many studies have been attempted to assess the significance of usage (142)Pr in radionuclide therapy. In many studies, the dosimetric parameters of (142)Pr sources were calcul...

journal_title：Annals of nuclear medicine

authors： Bakht MK,Jabal-Ameli H,Ahmadi SJ,Sadeghi M,Sadjadi S,Tenreiro C

更新日期：2012-06-01 00:00:00

abstract：PURPOSE:The aim of this study was to elucidate the regional differences between brain perfusion single photon emission computed tomography (SPECT) images reconstructed with a uniform attenuation correction using Chang's method (AC-Chang) and a non-uniform attenuation correction with CT using SPECT/CT (AC-CT). METHODS:...

journal_title：Annals of nuclear medicine

authors： Ishii K,Hanaoka K,Okada M,Kumano S,Komeya Y,Tsuchiya N,Hosono M,Murakami T

更新日期：2012-04-01 00:00:00

abstract：AIM:The motion of the head during brain positron emission tomography (PET) acquisitions has been identified as a source of artifact in the reconstructed image. In this study, a method is described to develop an image-based motion correction technique for correcting the post-acquisition data without using external optic...

journal_title：Annals of nuclear medicine

authors： Nazarparvar B,Shamsaei M,Rajabi H

更新日期：2012-01-01 00:00:00

abstract：OBJECTIVE:To investigate the genotoxic effects of (90)Y and (186)Re in patients with hemophilia who were undergoing radionuclide synovectomy (RS) procedure in the last 3 years. METHODS:Nineteen patients were enrolled in the study. Most of the patients (n = 17) were hemophilia-A (mean age 20.6 ± 10.5 years) and 18 pati...

journal_title：Annals of nuclear medicine

authors： Kavakli K,Cogulu O,Karaca E,Durmaz B,Ozkinay F,Aydogdu S,Ozkilic H,Balkan C,Karapinar D,Ay Y

更新日期：2012-01-01 00:00:00

abstract：OBJECTIVE:Metabolic tumor burden (MTB) incorporates the advantages of the existing indices: the metabolic volume of the lesion calculated by size-dependent thresholding on positron emission tomography-computed tomography (PET-CT) along with its aggressiveness as determined by standardized uptake value (SUV). This study...

journal_title：Annals of nuclear medicine

authors： Sharma P,Gupta A,Patel C,Bakhshi S,Malhotra A,Kumar R

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:Exact localization of recurrent iodine-negative thyroid cancer is mandatory, since surgery is the only curative therapy option in patients with iodine-negative tumor tissue. The aim of this study was to evaluate the impact of (18)F-FDG-PET/CT as a routine diagnostic tool on clinical management in patients wi...

journal_title：Annals of nuclear medicine

authors： Bannas P,Derlin T,Groth M,Apostolova I,Adam G,Mester J,Klutmann S

更新日期：2012-01-01 00:00:00

abstract：OBJECTIVES:Cardiac resynchronization therapy (CRT) is the established treatment for patients with chronic and severe heart failure, and it has been reported that the presence of left ventricular (LV) dyssynchrony is one of the most important factors which predict positive response of this therapy. In the present study,...

journal_title：Annals of nuclear medicine

authors： Kiso K,Imoto A,Nishimura Y,Kanzaki H,Noda T,Kamakura S,Ishida Y

更新日期：2011-12-01 00:00:00

abstract：OBJECTIVE:This study aims to determine whether a (131)I double-phase whole body scan (WBS) and SPECT-CT images have added value over a single-phase WBS image in identifying benign and malignant lesions in patients with well-differentiated thyroid cancer (DTC) at their first radioactive iodine (RAI) treatment. METHODS:...

journal_title：Annals of nuclear medicine

authors： Wakabayashi H,Nakajima K,Fukuoka M,Inaki A,Nakamura A,Kayano D,Kinuya S

更新日期：2011-11-01 00:00:00

abstract：OBJECTIVE:123I-beta-methyl iodophenyl pentadecanoic acid (BMIPP) can visualize myocardial fatty acid metabolism and has extensive potential for diagnosing cardiac diseases such as acute coronary syndrome in the clinical setting. Increased BMIPP uptake with decreased perfusion occasionally occurs under acute reperfusion...

journal_title：Annals of nuclear medicine

authors： Fukushima K,Momose M,Kondo C,Hagiwara N,Sakai S

更新日期：2011-10-01 00:00:00